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Registro Completo |
Biblioteca(s): |
Embrapa Arroz e Feijão. |
Data corrente: |
22/02/2006 |
Data da última atualização: |
23/02/2006 |
Autoria: |
RIBEIRO, A. de O.; BEARZOTI, E.; SÁFADI, T. |
Título: |
QTL mapping of Poisson traits: a simulation study. |
Ano de publicação: |
2005 |
Fonte/Imprenta: |
Crop Breeding and Applied Biotechnology, Viçosa, MG, v. 5, n. 3, p. 310-317, Sept. 2005. |
Idioma: |
Inglês |
Conteúdo: |
QTL mapping consists of estimating the position and effects of genes (or linkage groups) that control quantitative traits. For traits that follow a normal distribution of probability, statistical approaches for QTL mapping are described in literature. However, for other traits the amount of research is little. The present work aimed to evaluate four alternative methods for QTL mapping of genes that control Poisson traits. The studied approaches were: standard interval mapping methodologies of Lander and Botstein and of Haley and Knott, a mixed model based on Poisson distributions, and a generalized linear model. Through computational simulation, the results showed great similarity for the different approaches under study. All approaches were highly effective for the tested simulations, especially when the abnormality of data in use was taken into account. Owing to the computational simplicity, Harley and Knott's methodology was considered most effective.. |
Palavras-Chave: |
Distribuição de Poisson; Mapeamento de QTL; QTL mapping; Simulation. |
Thesagro: |
Simulação. |
Thesaurus Nal: |
Poisson distribution. |
Categoria do assunto: |
-- |
Marc: |
LEADER 01589naa a2200217 a 4500 001 1213878 005 2006-02-23 008 2005 bl uuuu u00u1 u #d 100 1 $aRIBEIRO, A. de O. 245 $aQTL mapping of Poisson traits$ba simulation study. 260 $c2005 520 $aQTL mapping consists of estimating the position and effects of genes (or linkage groups) that control quantitative traits. For traits that follow a normal distribution of probability, statistical approaches for QTL mapping are described in literature. However, for other traits the amount of research is little. The present work aimed to evaluate four alternative methods for QTL mapping of genes that control Poisson traits. The studied approaches were: standard interval mapping methodologies of Lander and Botstein and of Haley and Knott, a mixed model based on Poisson distributions, and a generalized linear model. Through computational simulation, the results showed great similarity for the different approaches under study. All approaches were highly effective for the tested simulations, especially when the abnormality of data in use was taken into account. Owing to the computational simplicity, Harley and Knott's methodology was considered most effective.. 650 $aPoisson distribution 650 $aSimulação 653 $aDistribuição de Poisson 653 $aMapeamento de QTL 653 $aQTL mapping 653 $aSimulation 700 1 $aBEARZOTI, E. 700 1 $aSÁFADI, T. 773 $tCrop Breeding and Applied Biotechnology, Viçosa, MG$gv. 5, n. 3, p. 310-317, Sept. 2005.
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Embrapa Arroz e Feijão (CNPAF) |
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